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Article

Association of angiotensin-converting enzyme (ACE) gene polymorphism with elevated serum ACE activity and major depression in an Iranian population.

Psychiatry research - 30 Dec 2012

Firouzabadi Negar, Shafiei Massoumeh, Bahramali Ehsan, Ebrahimi Soltan Ahmed, Bakhshandeh Hooman, Tajik Nader

Abstract excerpt

Genetic factors contribute substantially to the likelihood of developing major depressive disorder (MDD). The importance of renin-angiotensin system (RAS) elements in cognition and behaviour and their involvement in aetiology and treatment of depression imply that RAS gene polymorphism(s) associated with RAS overactivity might also be associated with depression. In the present study, genotype and allele...

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PMID: 22688325
DOI: 10.1016/j.psychres.2012.05.002

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ACE

Variants

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