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Article

When Genome Maintenance Goes Badly Awry.

Molecular cell - 2 Jun 2016

Kass Elizabeth M, Moynahan Mary Ellen, Jasin Maria

Abstract excerpt

Genetic abnormalities are present in all tumor types, although the frequency and type can vary. Chromosome abnormalities include highly aberrant structures, particularly chromothriptic chromosomes. The generation of massive sequencing data has illuminated the scope of the mutational burden in cancer genomes, identifying patterns of mutations (mutation signatures), which have the potential to shed light on the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27259208
DOI: 10.1016/j.molcel.2016.05.021
PMCID: PMC4966655

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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