Article
Translating insights from the cancer genome into clinical practice.
Nature - 3 Apr 2008
Chin Lynda, Gray Joe W
Abstract excerpt
Cancer cells have diverse biological capabilities that are conferred by numerous genetic aberrations and epigenetic modifications. Today's powerful technologies are enabling these changes to the genome to be catalogued in detail. Tomorrow is likely to bring a complete atlas of the reversible and irreversible alterations that occur in individual cancers. The challenge now is to work out which molecular...
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