Article
Exploring the genomes of cancer cells: progress and promise.
Science (New York, N.Y.) - 25 Mar 2011
Stratton Michael R
Abstract excerpt
The description and interpretation of genomic abnormalities in cancer cells have been at the heart of cancer research for more than a century. With exhaustive sequencing of cancer genomes across a wide range of human tumors well under way, we are now entering the end game of this mission. In the forthcoming decade, essentially complete catalogs of somatic mutations will be generated for tens of thousands of human...
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