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Article

Conditional knockout of retinal determination genes in differentiating cells in Drosophila.

The FEBS journal - 1 Aug 2016

Jin Meng, Eblimit Aiden, Pulikkathara Merlyn, Corr Stuart, Chen Rui, Mardon Graeme

Abstract excerpt

Conditional gene knockout in postmitotic cells is a valuable technique which allows the study of gene function with spatiotemporal control. Surprisingly, in contrast to its long-term and extensive use in mouse studies, this technology is lacking in Drosophila. Here, we use a novel method for generating complete loss of eyes absent (eya) or sine oculis (so) function in postmitotic cells posterior to the...

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Identifiers

PMID: 27257739
DOI: 10.1111/febs.13772
PMCID: PMC4975629

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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