Article
Genetic mosaic screens in Drosophila mushroom bodies.
Cold Spring Harbor protocols - 1 Jan 2013
Kao Chih-Fei, Lee Tzumin
Abstract excerpt
Genetic mosaics in Drosophila typically involve derivation of homozygous daughter cells from heterozygous precursors through mitotic recombination. MARCM (mosaic analysis with a repressible cell marker) couples loss of heterozygosity with derepression of a marker gene, permitting unique labeling of specific homozygous daughter cells. The generation of GAL80-minus homozygous daughter cells in otherwise...
Topics
- Animals
- Drosophila
- Genetic Testing
- Mosaicism
- Mushroom Bodies
- Mutation