Article
A genetic method for generating Drosophila eyes composed exclusively of mitotic clones of a single genotype.
Genetics - 1 Aug 1999
Stowers R S, Schwarz T L
Abstract excerpt
The genetic analysis of a gene at a late developmental stage can be impeded if the gene is required at an earlier developmental stage. The construction of mosaic animals, particularly in Drosophila, has been a means to overcome this obstacle. However, the phenotypic analysis of mitotic clones is often complicated because standard methods for generating mitotic clones render mosaic tissues that are a composite of...
Topics
- Animals
- Calcium-Binding Proteins
- Cell Lineage
- Chromosomes
- Clone Cells
- Crosses, Genetic
- Drosophila melanogaster
- Electroretinography
- Eye
- Genes, Lethal
- Genetic Techniques
- Genotype
- Insect Proteins
- Membrane Glycoproteins
- Membrane Proteins
- Microscopy, Electron, Scanning
- Mosaicism
- Nerve Tissue Proteins
