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Article

Genetic variation and cognitive dysfunction in opioid-treated patients with cancer.

Brain and behavior - 1 Jul 2016

Kurita Geana Paula, Ekholm Ola, Kaasa Stein, Klepstad Pål, Skorpen Frank, Sjøgren Per

Abstract excerpt

BACKGROUND AND PURPOSE: The effects of single-nucleotide polymorphisms (SNPs) on the cognitive function of opioid-treated patients with cancer until now have not been explored, but they could potentially be related to poor functioning. This study aimed at identifying associations between SNPs of candidate genes, high opioid dose, and cognitive dysfunction. METHODS: Cross-sectional multicenter study (European...

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Identifiers

PMID: 27247849
DOI: 10.1002/brb3.471
PMCID: PMC4864175

Genes

TACR1
TLR5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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