Article
Plasma 25-Hydroxyvitamin D, Vitamin D Binding Protein, and Risk of Colorectal Cancer in the Nurses' Health Study.
Cancer prevention research (Philadelphia, Pa.) - 1 Aug 2016
Song Mingyang, Konijeti Gauree Gupta, Yuan Chen, Ananthakrishnan Ashwin N, Ogino Shuji, Fuchs Charles S, Giovannucci Edward L, Ng Kimmie, Chan Andrew T
Abstract excerpt
Total circulating 25-hydroxyvitamin D [25(OH)D)] has been associated with lower risk of colorectal cancer. The physiologic mechanism, however, may be more directly related to the free or bioavailable fraction of 25(OH)D, which is influenced by levels of vitamin D binding protein (VDBP). We assessed the association of prediagnosis total, free, and bioavailable 25(OH)D and VDBP with colorectal cancer risk among...
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