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Article

Serum 25-hydroxyvitamin D, vitamin D-related variants, and risk of chronic liver disease.

International journal of cancer - 1 Nov 2025

Shen Qian, Shi Shanshan, Wang Haoxue, Zhang Shanshan, Qin Shifan, Sheng Xia, Chang Jiang, Zhang Xuehong, Cheng Xiang, Zhong Rong

Abstract excerpt

The associations of serum 25-hydroxyvitamin D (25(OH)D) with cirrhosis and liver cancer have not been well examined. It remained unclear whether functional vitamin D-related variants modify these associations. During follow-up of 401,551 UK Biobank participants with valid 25(OH)D data, we documented 4404 incident non-alcoholic fatty liver disease (NAFLD), 1989 incident cirrhosis, and 480 incident liver cancer....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 40515575
DOI: 10.1002/ijc.35522

Genes

VDR
GC

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