Article
Dupuytren's disease susceptibility gene, EPDR1, is involved in myofibroblast contractility.
Journal of dermatological science - 1 Aug 2016
Staats Kim A, Wu Timothy, Gan Bing S, O'Gorman David B, Ophoff Roel A
Abstract excerpt
BACKGROUND: Dupuytren's Disease is a common disorder of the connective tissue characterized by progressive and irreversible fibroblastic proliferation affecting the palmar fascia. Progressive flexion deformity appears over several months or years and although usually painless, it can result in a serious handicap causing loss of manual dexterity. There is no cure for the disease and the etiology is largely...
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