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Article

Evaluating the contribution of APOBEC3G haplotypes, on influencing HIV infection in a Zimbabwean paediatric population.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde - 25 May 2016

Mhandire K, Duri K, Mhandire D, Musarurwa C, Stray-Pedersen B, Dandara C

Abstract excerpt

BACKGROUND: Apolipoprotein B mRNA-editing catalytic polypeptide like-3G (APOBEC3G) is an antiviral enzyme that reduces viral fitness by introducing uracil to thymidine hypermutations in viral genomes. Thus, polymorphisms in the APOBEC3G gene have been implicated in differential outcomes of HIV infection and disease progression. However, there is insufficient evidence on the role of APOBEC3G gene variants on HIV...

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Identifiers

PMID: 27245545
DOI: 10.7196/SAMJ.2016.v106i6.11013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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