Article
Prognostic value of the stromal cell-derived factor 1 3'A mutation in pediatric human immunodeficiency virus type 1 infection.
The Journal of infectious diseases - 1 Mar 2002
Tresoldi Eleonora, Romiti Maria Luisa, Boniotto Michele, Crovella Sergio, Salvatori Francesca, Palomba Elvia, Pastore Angela, Cancrini Caterina, de Martino Maurizio, Plebani Anna, Castelli Guido, Rossi Paolo, Tovo Pier Angelo, Amoroso Antonio, Scarlatti Gabriella
Abstract excerpt
A mutation of the stromal cell-derived factor 1 gene (SDF-1 3'A) was shown to protect adults exposed to human immunodeficiency virus type 1 (HIV-1) from infection and to affect HIV disease progression in adults. The presence of this mutation in HIV-1-infected Kenyan children did not predict mother-to-child virus transmission. The SDF-1 3'A polymorphism was studied in 256 HIV-1-infected, 118 HIV-1-exposed but...
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