Article
How does mother-to-child transmission of HIV differ among African populations? Lessons from MBL2 genetic variation in Zimbabweans.
Omics : a journal of integrative biology - 1 Jul 2014
Mhandire Kudakwashe, Pharo Gavin, Kandawasvika Gwendolene Q, Duri Kerina, Swart Marelize, Stray-Pedersen Babill, Dandara Collet
Abstract excerpt
Mannose binding lectin (MBL) is a pathogen pattern recognition protein involved in antimicrobial activities. Variation in MBL2 gene has been extensively implicated in differential outcomes of infectious diseases in studies conducted outside Africa, but virtually very little is known on the role of this candidate gene in the African continent. We investigated human genetic variations in MBL2 in a Zimbabwean...
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