Article
Mutational signature of aristolochic acid: Clue to the recognition of a global disease.
DNA repair - 1 Aug 2016
Rosenquist Thomas A, Grollman Arthur P
Abstract excerpt
Mutational signatures associated with specific forms of DNA damage have been identified in several forms of human cancer. Such signatures provide information regarding mechanisms of tumor induction which, in turn, can reduce exposure to carcinogens by shaping public health policy. Using a molecular epidemiologic approach that takes advantage of recent advances in genome sequencing while applying sensitive and...
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