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Article

Tryptophan hydroxylase type 2 variants modulate severity and outcome of addictive behaviors in Parkinson's disease.

Parkinsonism & related disorders - 1 Aug 2016

Cilia Roberto, Benfante Roberta, Asselta Rosanna, Marabini Laura, Cereda Emanuele, Siri Chiara, Pezzoli Gianni, Goldwurm Stefano, Fornasari Diego

Abstract excerpt

BACKGROUND: Impulse control disorders and compulsive medication intake may occur in a minority of patients with Parkinson's disease (PD). We hypothesize that genetic polymorphisms associated with addiction in the general population may increase the risk for addictive behaviors also in PD. METHODS: Sixteen polymorphisms in candidate genes belonging to five neurotransmitter systems (dopaminergic, catecholaminergic,...

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Source

Identifiers

PMID: 27237108
DOI: 10.1016/j.parkreldis.2016.05.017

Genes

TPH2
BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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