Article
Exome-based proteogenomics of HEK-293 human cell line: Coding genomic variants identified at the level of shotgun proteome.
Proteomics - 1 Jul 2016
Lobas Anna A, Karpov Dmitry S, Kopylov Arthur T, Solovyeva Elizaveta M, Ivanov Mark V, Ilina Irina Y, Lazarev Vassily N, Kuznetsova Ksenia G, Ilgisonis Ekaterina V, Zgoda Victor G, Gorshkov Mikhail V, Moshkovskii Sergei A
Abstract excerpt
Genomic and proteomic data were integrated into the proteogenomic workflow to identify coding genomic variants of Human Embryonic Kidney 293 (HEK-293) cell line at the proteome level. Shotgun proteome data published by Geiger et al. (2012), Chick et al. (2015), and obtained in this work for HEK-293 were searched against the customized genomic database generated using exome data published by Lin et al. (2014)....
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