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Article

Exome-driven characterization of the cancer cell lines at the proteome level: the NCI-60 case study.

Journal of proteome research - 5 Dec 2014

Karpova Maria A, Karpov Dmitry S, Ivanov Mark V, Pyatnitskiy Mikhail A, Chernobrovkin Alexey L, Lobas Anna A, Lisitsa Andrey V, Archakov Alexander I, Gorshkov Mikhail V, Moshkovskii Sergei A

Abstract excerpt

Cancer genome deviates significantly from the reference human genome, and thus a search against standard genome databases in cancer cell proteomics fails to identify cancer-specific protein variants. The goal of this Article is to combine high-throughput exome data [Abaan et al. Cancer Res. 2013] and shotgun proteomics analysis [Modhaddas Gholami et al. Cell Rep. 2013] for cancer cell lines from NCI-60 panel to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25333775
DOI: 10.1021/pr500531x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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