Article

CusVarDB: A tool for building customized sample-specific variant protein database from next-generation sequencing datasets

2020-11-16

Abstract excerpt

Cancer genome sequencing studies have revealed a number of variants in coding regions of several genes. Some of these coding variants play an important role in activating specific pathways that drive proliferation. Coding variants present on cancer cell surfaces by the major histocompatibility complex serve as neo-antigens and result in immune activation. The success of immune therapy in patients is attributed to...

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Literature Corpus work: f362f933-b8f6-5f99-8d60-e519739367c6
DOI: 10.12688/f1000research.23214.2

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