Article
Cell-Envelope Remodeling as a Determinant of Phenotypic Antibacterial Tolerance in <i>Mycobacterium tuberculosis</i>
29 Mar 2016
Abstract excerpt
High Resolution Image Download MS PowerPoint Slide The mechanisms that lead to phenotypic antibacterial tolerance in bacteria remain poorly understood. We investigate whether changes in NaCl concentration toward physiologically higher values affect antibacterial efficacy against Mycobacterium tuberculosis (Mtb), the causal agent of human tuberculosis. Indeed, multiclass phenotypic antibacterial tolerance is...
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