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Article

Identification of Causative Variants Contributing to Nonsyndromic Orofacial Clefts Using Whole-Exome Sequencing in a Saudi Family.

Genetic testing and molecular biomarkers - 1 Nov 2020

Al Mahdi Hadiah Bassam, Edris Sherif, Bahieldin Ahmed, Al-Aama Jumana Y, Elango Ramu, Jamalalail Bassam Adnan, Sabbagh Heba Jafar

Abstract excerpt

Objectives: Nonsyndromic orofacial clefts (NSOFCs) are the most common craniofacial malformations observed across the globe. They are classified into three types: (a) cleft palate, (b) cleft lip, and (c) cleft lip and palate. To identify the potential candidate genes contributing to polygenic diseases such as NSOFC, linkage analyses, genome-wide association studies, and genomic rearrangements can be used. Genomic...

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Identifiers

PMID: 33121284
DOI: 10.1089/gtmb.2019.0233

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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