Article
Allele-specific expression of mutated in colorectal cancer (MCC) gene and alternative susceptibility to colorectal cancer in schizophrenia.
Scientific reports - 26 May 2016
Wang Yang, Cao Yanfei, Huang Xiaoye, Yu Tao, Wei Zhiyun, McGrath John, Xu Fei, Bi Yan, Li Xingwang, Yang Fengping, Li Weidong, Zou Xia, Peng Zhihai, Xiao Yanzeng, Zhang Yan, He Lin, He Guang
Abstract excerpt
Evidence has indicated that the incidence of colorectal cancer (CRC) among schizophrenia is lower than normal. To explore this potential protective effect, we employed an innovative strategy combining association study with allele-specific expression (ASE) analysis in MCC gene. We first genotyped four polymorphisms within MCC in 312 CRC patients, 270 schizophrenia patients and 270 controls. Using the MassArray...
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