Article
The tumor suppressor adenomatous polyposis coli gene is associated with susceptibility to schizophrenia.
Molecular psychiatry - 1 Jul 2005
Cui D H, Jiang K D, Jiang S D, Xu Y F, Yao H
Abstract excerpt
The etiology of schizophrenia is unclear, although family, twin, and linkage studies implicate genetic factors. Here, we identified adenomatous polyposis coli (APC), a tumor suppressor gene, as a risk factor for schizophrenia. We compared leukocytic gene expression patterns of six pairs of patients with schizophrenia and healthy controls by microarray. APC expression levels were significantly increased in all...
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