Article
Polymorphisms of XRCC4 are involved in reduced colorectal cancer risk in Chinese schizophrenia patients.
BMC cancer - 4 Oct 2010
Wang Yang, Wang Lei, Li Xingwang, Liu Baocheng, Zhao Qingzhu, Chen Peng, Wang Ti, Li Tao, Ji Jue, Yang Fengping, Wang Quan, Wang Jinfen, Xiao Yanzeng, Xu Yifeng, Feng Guoyin, Peng Zhihai, He Lin, He Guang
Abstract excerpt
BACKGROUND: Genetic factors related to the regulation of apoptosis in schizophrenia patients may be involved in a reduced vulnerability to cancer. XRCC4 is one of the potential candidate genes associated with schizophrenia which might induce colorectal cancer resistance. METHODS: To examine the genetic association between colorectal cancer and schizophrenia, we analyzed five SNPs (rs6452526, rs2662238, rs963248,...
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