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Article

A genetic polymorphism affects the risk and prognosis of renal cell carcinoma: association with follistatin-like protein 1 expression.

Scientific reports - 26 May 2016

Liu Yan, Han Xue, Yu Yongwei, Ding Yibo, Ni Chong, Liu Wenbin, Hou Xiaomei, Li Zixiong, Hou Jianguo, Shen Dan, Yin Jianhua, Zhang Hongwei, Thompson Timothy C, Tan Xiaojie, Cao Guangwen

Abstract excerpt

Few single nucleotide polymorphisms (SNPs) associated with the risk of renal cell carcinoma (RCC) have been identified, yet genetic predisposition contributes significantly to this malignancy. We previously showed that follistatin-like 1 (FSTL1) was significantly down-regulated in clear cell RCC (ccRCC), in particular metastatic ccRCC. In the present study, we systemically investigated the associations of the 6...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27225192
DOI: 10.1038/srep26689
PMCID: PMC4880907

Genes

FSTL1
CTCF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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