Article
Genetic scores based on risk-associated single nucleotide polymorphisms (SNPs) can reveal inherited risk of renal cell carcinoma.
Oncotarget - 5 Apr 2016
Wu Yishuo, Zhang Ning, Li Kaiwen, Chen Haitao, Lin Xiaolin, Yu Yang, Gou Yuancheng, Hou Jiangang, Jiang Deke, Na Rong, Wang Xiang, Ding Qiang, Xu Jianfeng
Abstract excerpt
The objective of this study was to evaluate whether renal cell carcinoma (RCC) risk-associated single nucleotide polymorphisms (SNPs) could reflect the individual inherited risks of RCC. A total of 346 RCC patients and 1,130 controls were recruited in this case-control study. Genetic scores were calculated for each individual based on the odds ratios and frequencies of risk-associated SNPs. Four SNPs were...
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