Functional promoter -31G>C variant in survivin gene is associated with risk and progression of renal cell cancer in a Chinese population.

doi:10.1371/journal.pone.0028829

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Article

Functional promoter -31G>C variant in survivin gene is associated with risk and progression of renal cell cancer in a Chinese population.

PloS one - 1 Jan 2012

Qin Chao, Cao Qiang, Li Pu, Ju Xiaobing, Wang Meilin, Chen Jiawei, Wu Yilong, Meng Xiaoxin, Zhu Jian, Zhang Zhengdong, Lu Qiang, Yin Changjun

Abstract excerpt

BACKGROUND: Survivin is an inhibitor of apoptosis protein and is involved in the occurrence and progression of human malignancies. Recently, a functional polymorphism (-31G>C, rs9904341) in the promoter of survivin has been shown to influence its expression and confer susceptibility to different types of cancer. The present study was aimed to investigate whether the polymorphism also influences susceptibility and...

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Identifiers

PMID: 22295057
DOI: 10.1371/journal.pone.0028829
PMCID: PMC3266235

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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