Article
Polymorphism of the follistatin gene in polycystic ovary syndrome.
Molecular human reproduction - 1 Apr 2007
Jones M R, Wilson S G, Mullin B H, Mead R, Watts G F, Stuckey B G A
Abstract excerpt
Follistatin has been reported as a candidate gene for polycystic ovary syndrome (PCOS) from linkage and association studies. Acting to regulate the development of ovarian follicles and as an antagonist to aromatase activity, alterations in follistatin function or expression may result in key features of PCOS such as reduced serum FSH, impaired ovarian follicle development and augmented ovarian androgen...
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