Article
Analysis of the virulence determination mechanisms in a local Toxoplasma strain (T.gHB1) isolated from central China.
Parasitology research - 1 Oct 2016
Zhang Weichao, Li Longjiao, Xia Ningbo, Zhou Yanqin, Fang Rui, He Lan, Hu Min, Shen Bang, Zhao Junlong
Abstract excerpt
Several rhoptry proteins (ROPs) have been confirmed to be critical virulence factors of Toxoplasma gondii strains from North America and Europe. The two active kinases ROP17 and ROP18, and pseudokinase ROP5 were thought to be the key determinants of parasites' virulence in laboratory mice. Given the genetic diversity of Toxoplasma strains from different geographical regions, the virulence determinants in other...
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