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Molecular and biological analysis revealed genetic diversity and high virulence strain of Toxoplasma gondii in Japan.

PloS one - 1 Jan 2020

Fukumoto Junpei, Yamano Akinori, Matsuzaki Motomichi, Kyan Hisako, Masatani Tatsunori, Matsuo Tomohide, Matsui Toshihiro, Murakami Mami, Takashima Yasuhiro, Matsubara Ryuma, Tahara Michiru, Sakura Takaya, Takeuchi Fumihiko, Nagamune Kisaburo

Abstract excerpt

Toxoplasma gondii is classified into 16 haplogroups based on a worldwide genotyping study of the parasite. However, only a few isolates from Japan were included in this analysis. To conduct more precise genotyping of T. gondii, we examined the genotypes of Japanese isolates in this study. DNA sequences of 6 loci were determined in 17 Japanese isolates and compared with those of strains of 16 haplogroups. As a...

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PMID: 32012177
DOI: 10.1371/journal.pone.0227749
PMCID: PMC6996823

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