Article
Transcriptome landmarks of the functional maturity of rat beta-cells, from lactation to adulthood.
Journal of molecular endocrinology - 1 Jul 2016
Larqué Carlos, Velasco Myrian, Barajas-Olmos Francisco, García-Delgado Neyvis, Chávez-Maldonado Juan Pablo, García-Morales Jazmín, Orozco Lorena, Hiriart Marcia
Abstract excerpt
Research on the postnatal development of pancreatic beta-cells has become an important subject in recent years. Understanding the mechanisms that govern beta-cell postnatal maturation could bring new opportunities to therapeutic approaches for diabetes. The weaning period consists of a critical postnatal window for structural and physiologic maturation of rat beta-cells. To investigate transcriptome changes...
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