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Article

Sex differences underlying pancreatic islet biology and its dysfunction

30 May 2018

Abstract excerpt

BACKGROUND: The sex of an individual affects glucose homeostasis and the pathophysiology, incidence, and prevalence of diabetes as well as the response to therapy. SCOPE OF THE REVIEW: This review focuses on clinical and experimental sex differences in islet cell biology and dysfunction during development and in adulthood in human and animal models. We discuss sex differences in β-cell and α-cell function,...

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Share to Diabetes and associated disorders
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Identifiers

PMID: 29891438
DOI: 10.1016/j.molmet.2018.05.017

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