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Article

Developmental suppression of schizophrenia-associated miR-137 alters sensorimotor function in zebrafish.

Translational psychiatry - 24 May 2016

Giacomotto J, Carroll A P, Rinkwitz S, Mowry B, Cairns M J, Becker T S

Abstract excerpt

The neurodevelopmentally regulated microRNA miR-137 was strongly implicated as risk locus for schizophrenia in the most recent genome wide association study coordinated by the Psychiatric Genome Consortium (PGC). This molecule is highly conserved in vertebrates enabling the investigation of its function in the developing zebrafish. We utilized this model system to achieve overexpression and suppression of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27219344
DOI: 10.1038/tp.2016.88
PMCID: PMC5070046

Genes

PGC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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