Article
A direct molecular link between the autism candidate gene RORa and the schizophrenia candidate MIR137.
Scientific reports - 6 Feb 2014
Devanna Paolo, Vernes Sonja C
Abstract excerpt
Retinoic acid-related orphan receptor alpha gene (RORa) and the microRNA MIR137 have both recently been identified as novel candidate genes for neuropsychiatric disorders. RORa encodes a ligand-dependent orphan nuclear receptor that acts as a transcriptional regulator and miR-137 is a brain enriched small non-coding RNA that interacts with gene transcripts to control protein levels. Given the mounting evidence...
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