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Article

Cytokine-induced killer cells interact with tumor lysate-pulsed dendritic cells via CCR5 signaling.

Cancer letters - 10 Aug 2016

Lee Hong Kyung, Kim Yong Guk, Kim Ji Sung, Park Eun Jae, Kim Boyeong, Park Ki Hwan, Kang Jong Soon, Hong Jin Tae, Kim Youngsoo, Han Sang-Bae

Abstract excerpt

The antitumor activity of cytokine-induced killer (CIK) cells can be increased by co-culturing them with tumor lysate-pulsed dendritic cells (tDCs); this phenomenon has been studied mainly at the population level. Using time-lapse imaging, we examined how CIK cells gather information from tDCs at the single-cell level. tDCs highly expressed CCL5, which bound CCR5 expressed on CIK cells. tDCs strongly induced...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27216980
DOI: 10.1016/j.canlet.2016.05.020

Genes

CCR5
CCL5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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