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Article

Capturing T Lymphocytes' Dynamic Interactions With Human Neural Cells Using Time-Lapse Microscopy.

Frontiers in immunology - 1 Jan 2021

Lemaître Florent, Carmena Moratalla Ana, Farzam-Kia Negar, Carpentier Solorio Yves, Tastet Olivier, Cleret-Buhot Aurélie, Guimond Jean Victor, Haddad Elie, Arbour Nathalie

Abstract excerpt

To fully perform their functions, T lymphocytes migrate within organs' parenchyma and interact with local cells. Infiltration of T lymphocytes within the central nervous system (CNS) is associated with numerous neurodegenerative disorders. Nevertheless, how these immune cells communicate and respond to neural cells remains unresolved. To investigate the behavior of T lymphocytes that reach the CNS, we have...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33968073
DOI: 10.3389/fimmu.2021.668483
PMCID: PMC8100528

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