Article

CAR-MACROPHAGES ACTIVATE ANTI TUMOR T CELLS IN THE ABSENCE OF PHAGOCYTOSIS

2026-03-12

Abstract excerpt

<h4>ABSTRACT</h4> Macrophages are highly abundant within the tumor microenvironment and serve as an essential bridge between innate and adaptive immune responses. Thus, they have emerged as promising candidates for chimeric antigen receptor (CAR)-based therapeutic strategies. Previous studies demonstrated that adenovirally-transduced CAR-macrophages (CAR-M), used in clinical trials, can perform tumor cell phagocy...

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Literature Corpus work: 8a7f98e7-7545-5678-9a35-4ac6d351cdc5
DOI: 10.64898/2026.03.11.710792

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