Article
Phenotypic Characterization of a Leishmania donovani Cyclophilin 40 Null Mutant.
The Journal of eukaryotic microbiology - 1 Nov 2016
Yau Wai-Lok, Lambertz Ulrike, Colineau Lucie, Pescher Pascale, MacDonald Andrea, Zander Dorothea, Retzlaff Silke, Eick Julia, Reiner Neil E, Clos Joachim, Späth Gerald F
Abstract excerpt
Protozoan parasites of the genus Leishmania adapt to their arthropod and vertebrate hosts through the development of defined life cycle stages. Stage differentiation is triggered by environmental stress factors and has been linked to parasite chaperone activities. Using a null mutant approach we previously revealed important, nonredundant functions of the cochaperone cyclophilin 40 in L. donovani-infected...
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