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Article

CYP5122A1, a Novel Cytochrome P450 Is Essential for Survival of Leishmania donovani

23 Sept 2011

Abstract excerpt

BACKGROUND: Cytochrome P450s (CYP450s) are hemoproteins catalysing diverse biochemical reactions important for metabolism of xenobiotics and synthesis of physiologically important compounds such as sterols. Therefore, they are functionally important for survival of invading pathogens. One such opportunistic pathogen Leishmania donovani causes visceral leishmaniasis worldwide, which is an important public health...

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PMID: 21966477
DOI: 10.1371/journal.pone.0025273

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