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Article

Correlation Study Between IL-28B Gene Polymorphism (rs8099917SNP) and Sustained Virological Response in Iranian Patients with Chronic Hepatitis C.

Clinical laboratory - 1 Jan 2016

Larijani Mona Sadat, Sadat Seyed Mehdi, Nikbin Mehri, Talebi Seyedeh Solmaz, Javadi Foozieh, Mohajel Nasir, Bolhassani Azam, Daneshvar Mahtab, Aghasadeghi Mohammad Reza, Pouriayevali Mohammad Hassan, Mapar Maryam

Abstract excerpt

BACKGROUND: The current standard treatment for hepatitis C is a combination of pegylated interferon alpha and ribavirin (peg-IFNα/RBV). Recent studies have shown that single nucleotide polymorphisms (SNPs) near the interleukin 28B (IL28B) gene coding for IFN-λ3 were associated with the antiviral treatment response. Therefore, in this study, we determined the distribution of the rs8099917 (T/G) polymorphism with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 27156332
DOI: 10.7754/clin.lab.2015.150724

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