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Article

Critical effects on binding of epidermal growth factor produced by amino acid substitutions.

Journal of biomolecular structure & dynamics - 1 Apr 2017

Mehrabi Masomeh, Khodarahmi Reza, Shahlaei Mohsen

Abstract excerpt

Epidermal growth factor (EGF) plays important roles in multiple biological processes, such as the regulation of cell growth, proliferation, and differentiation. EGF exerts their pharmacologic effects via receptor-mediated mechanism associated with high affinity to epidermal growth factor receptor (EGFR) on the cell surface. Overexpression of EGFR has been reported and implicated in the pathogenesis of many human...

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Source

Identifiers

PMID: 27212100
DOI: 10.1080/07391102.2016.1171799

Genes

EGF
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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