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Article

Structural investigation of deleterious non-synonymous SNPs of EGFR gene.

Interdisciplinary sciences, computational life sciences - 1 Mar 2013

Raghav Dhwani, Sharma Vinay, Agarwal Subhash Mohan

Abstract excerpt

Epidermal Growth Factor Receptor (EGFR), a member of the receptor tyrosine kinase family has shown to be implicated in the development and progression of various cancers due to mutations in the tyrosine kinase domain (TKD). It is important to understand the functional significance of amino acid variation occurring within TKD due to non-synonymous Single Nucleotide Polymorphism (nsSNPs). Therefore, we have...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23605641
DOI: 10.1007/s12539-013-0149-x

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EGFR

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