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Article

Comprehensive Genomic Profiling of Clinically Advanced Medullary Thyroid Carcinoma.

Oncology - 1 Jan 2016

Heilmann Andreas M, Subbiah Vivek, Wang Kai, Sun James X, Elvin Julia A, Chmielecki Juliann, Sherman Steven I, Murthy Ravi, Busaidy Naifa L, Subbiah Ishwaria, Yelensky Roman, Nangia Chaitali, Vergilio Jo-Anne, Khan Saad A, Erlich Rachel L, Lipson Doron, Ross Jeffrey S, Miller Vincent A, Shah Manisha H, Ali Siraj M, Stephens Philip J

Abstract excerpt

OBJECTIVE: The aim of this study was to determine the genomic alterations of cancer-related genes in advanced medullary thyroid carcinoma during the course of clinical care. METHODS: Hybrid-capture-based comprehensive genomic profiling was performed on 34 consecutive medullary thyroid carcinoma cases to identify all four classes of genomic alterations, and outcome for an index patient was collected. RESULTS: RET...

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Source

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Identifiers

PMID: 27207748
DOI: 10.1159/000445978
PMCID: PMC4909575

Genes

RET
CCND1
FGF19
FGF3
HRAS
KRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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