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Article

Targeted therapy in thyroid cancer: molecular alterations and clinical management.

Frontiers in endocrinology - 1 Jan 2026

Yang YiHeng, Zhang YeSheng, Xu YongCan, Gu XiaoXin, Lou Neng, Ye GuoChao

Abstract excerpt

Background: This review summarizes key actionable molecular alterations in thyroid cancer and examines how molecular profiling can be translated into practical, subtype-specific targeted treatment strategies for advanced, recurrent, or radioiodine-refractory disease. Methods: A narrative synthesis was performed using evidence from landmark clinical trials, current consensus guidelines, and representative...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42325622
DOI: 10.3389/fendo.2026.1810813
PMCID: PMC13278885

Genes

BRAF
RET

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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