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Variants in Genes Controlling Oxidative Metabolism Contribute to Lower Hepatic ATP Independent of Liver Fat Content in Type 1 Diabetes.

Diabetes - 1 Jul 2016

Gancheva Sofiya, Bierwagen Alessandra, Kaul Kirti, Herder Christian, Nowotny Peter, Kahl Sabine, Giani Guido, Klueppelholz Birgit, Knebel Birgit, Begovatz Paul, Strassburger Klaus, Al-Hasani Hadi, Lundbom Jesper, Szendroedi Julia, Roden Michael

Abstract excerpt

Type 1 diabetes has been recently linked to nonalcoholic fatty liver disease (NAFLD), which is known to associate with insulin resistance, obesity, and type 2 diabetes. However, the role of insulin resistance and hyperglycemia for hepatic energy metabolism is yet unclear. To analyze early abnormalities in hepatic energy metabolism, we examined 55 patients with recently diagnosed type 1 diabetes. They underwent...

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PMID: 27207512
DOI: 10.2337/db16-0162

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PPARG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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