Article
Liver nucleotide biosynthesis is linked to protection from vascular complications in individuals with long-term type 1 diabetes.
Scientific reports - 14 Jul 2020
Jain Ruchi, Özgümüş Türküler, Jensen Troels Mygind, du Plessis Elsa, Keindl Magdalena, Møller Cathrine Laustrup, Falhammar Henrik, Nyström Thomas, Catrina Sergiu-Bogdan, Jörneskog Gun, Jessen Leon Eyrich, Forsblom Carol, Haukka Jani K, Groop Per-Henrik, Rossing Peter, Groop Leif, Eliasson Mats, Eliasson Björn, Brismar Kerstin, Al-Majdoub Mahmoud, Nilsson Peter M, Taskinen Marja-Riitta, Ferrannini Ele, Spégel Peter, Berg Tore Julsrud, Lyssenko Valeriya
Abstract excerpt
Identification of biomarkers associated with protection from developing diabetic complications is a prerequisite for an effective prevention and treatment. The aim of the present study was to identify clinical and plasma metabolite markers associated with freedom from vascular complications in people with very long duration of type 1 diabetes (T1D). Individuals with T1D, who despite having longer than 30 years of...
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