Article
Oncological miR-182-3p, a Novel Smooth Muscle Cell Phenotype Modulator, Evidences From Model Rats and Patients.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jul 2016
Sun Lan, Bai Yongyi, Zhao Rui, Sun Tao, Cao Ruihua, Wang Fuyu, He Guorong, Zhang Wen, Chen Ying, Ye Ping, Du Guanhua
Abstract excerpt
OBJECTIVE: Vascular smooth muscle cell (VSMC) phenotype change is a hallmark of vascular remodeling, which contributes to atherosclerotic diseases and can be regulated via microRNA-dependent mechanisms. We recently identified that asymmetrical dimethylarginine positively correlates to vascular remodeling-based diseases. We hypothesized that asymmetrical dimethylarginine induces smooth muscle cell (SMC) phenotypic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
