Persistence and drug tolerance in pathogenic yeast.

Abstract excerpt

In this review, we briefly summarize the current understanding of how fungal pathogens can persist antifungal treatment without heritable resistance mutations by forming tolerant persister cells. Fungal infections tolerant to antifungal treatment have become a major medical problem. One mechanism leading to drug recalcitrance is the formation of antifungal persister cells. These cells have wild-type genotype with...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Antifungal Agents
• Share to Candidiasis
• Share to Adaptation, Biological