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Article

Candida albicans biofilms produce antifungal-tolerant persister cells.

Antimicrobial agents and chemotherapy - 1 Nov 2006

LaFleur Michael D, Kumamoto Carol A, Lewis Kim

Abstract excerpt

Fungal pathogens form biofilms that are highly recalcitrant to antimicrobial therapy. The expression of multidrug resistance pumps in young biofilms has been linked to increased resistance to azoles, but this mechanism does not seem to underlie the resistance of mature biofilms that is a model of in vivo infection. The mechanism of drug resistance of mature biofilms remains largely unknown. We report that...

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Identifiers

PMID: 16923951
DOI: 10.1128/AAC.00684-06
PMCID: PMC1635216

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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