Article
Patients with long-term oral carriage harbor high-persister mutants of Candida albicans.
Antimicrobial agents and chemotherapy - 1 Jan 2010
Lafleur Michael D, Qi Qingguo, Lewis Kim
Abstract excerpt
Fungal biofilms produce a small number of persister cells which can tolerate high concentrations of fungicidal agents. Persisters form upon attachment to a surface, an important step in the pathogenesis of Candida strains. The periodic application of antimicrobial agents may select for strains with increased levels of persister cells. In order to test this possibility, 150 isolates of Candida albicans and C....
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